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Results for "

semi-synthetic antibiotic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (45) Apoptosis (3) Bacterial (45) Biochemical Assay Reagents (1) Calcium Channel (3) Fungal (1) HIF/HIF Prolyl-Hydroxylase (3) Isotope-Labeled Compounds (5) MDM-2/p53 (3) Parasite (2) Penicillin-binding protein (PBP) (8) Potassium Channel (3)
By Research Areas:	Cancer (15) Cardiovascular Disease (3) Infection (48) Inflammation/Immunology (4) Metabolic Disease (3) Neurological Disease (4)

Inhibitors & Agonists

Isotope-Labeled Compounds

Targets Recommended: Antibiotic

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0974

Methicillin sodium salt 4 Publications Verification Meticillin sodium	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection
Methicillin sodium salt (Meticillin sodium) is a β-lactam, semi-synthetic antibiotic related to penicillin antibiotic. Methicillin sodium salt inhibits penicillin-binding proteins involved in the synthesis of peptidoglycan. Methicillin sodium salt inhibits S. aureus with a MIC value of 2.1 μg/mL. Methicillin sodium salt can be used for the research of inflammation .

HY-B0435

Roxithromycin

4 Publications Verification

RU-28965
Bacterial Antibiotic Infection

Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic.

Roxithromycin 4 Publications Verification RU-28965	Bacterial Antibiotic	Infection
Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic.

HY-17466A

Sancycline hydrochloride Bonomycin hydrochloride; 6-Demethyl-6-deoxytetracycline hydrochloride	Antibiotic Bacterial	Infection
Sancycline (Bonomycin; 6-Demethyl-6-deoxytetracycline) hydrochloride is a semi-synthetic tetracycline antibiotic .

HY-A0241

Dalfopristin 2 Publications Verification RP54476	Bacterial Antibiotic	Infection
Dalfopristin is a semi-synthetic streptogramin antibiotic. Quinupristin/Dalfopristin (Q/D) is a valuable alternative antibiotic to vancomycin for the treatment of multi-agent resistant Enterococcus faecium infections.

HY-109125A

Amcipatricin L-aspartate SPA-S-753; SPA-S-752 L-aspartate	Antibiotic Fungal	Infection
Amcipatricin diaspartate (SPA-S-753) is a semi-synthetic polyene antibiotic, with potent broad-spectrum antifungal activity .

HY-161300

Antibacterial agent 191	Bacterial Antibiotic	Infection
Antibacterial agent 191 (compound 11a) is a potent semi-synthetic *antibiotic*. Antibacterial agent 191 exhibits preferable metabolic stability .

HY-148286

Gentamicin C1a	Antibiotic Bacterial	Infection
Gentamicin C1a is the precursor of the semi-synthetic *antibiotic* Etimicin, and has antibacterial activity. Gentamicin C1a is the major component of the Gentamicin complex .

HY-13234S

Rifaximin-d6	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Rifaximin-d₆ is the deuterium labeled Rifaximin. Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity[1][2].

HY-B0525

Carbenicillin	Antibiotic Bacterial	Infection
Carbenicillin is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin can interfere the cell wall synthesis while displaying low toxicity to plant tissue .

HY-17412S

Minocycline-d6 hydrochloride	Isotope-Labeled Compounds Antibiotic	Others
Minocycline-d₆ hydrochloride is deuterated labeled Minocycline hydrochloride (HY-17412). Minocycline hydrochloride is an orally effective semi-synthetic tetracycline antibiotic and HIF-1α inhibitor .

HY-B0643

Dirithromycin 1 Publications Verification LY237216	Bacterial Antibiotic	Infection
Dirithromycin (LY237216), a derivative of Erythromycin, is a potent and orally active semi-synthetic macrolide antibiotic. Dirithromycin is active against gram-positive bacteria, Legionella spp., Helicobacter pylori, and Chlamydia trachomatis .

HY-B0771

Cefozopran SCE-2787	Bacterial Antibiotic	Infection
Cefozopran (SCE-2787) is a semi-synthetic, parenteral, fourth-generation cephalosporin. Cefozopran, an antibiotic, has a broad spectrum of antibacterial activity, inhibiting most of the gram-negative and gram-positive organisms .

HY-B0525A

Carbenicillin disodium 4 Publications Verification Sodium carbenicillin	Antibiotic Bacterial	Infection
Carbenicillin disodium (Sodium carbenicillin) is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin disodium can interfere the cell wall synthesis while displaying low toxicity to plant tissue .

HY-B0771A

Cefozopran hydrochloride SCE-2787 hydrochloride	Bacterial Antibiotic	Infection
Cefozopran (SCE-2787) hydrochloride is a semi-synthetic, parenteral, fourth-generation cephalosporin. Cefozopran hydrochloride, an antibiotic, has a broad spectrum of antibacterial activity, inhibiting most of the gram-negative and gram-positive organisms .

HY-B0435S

Roxithromycin-d7 RU-28965-d₇	Isotope-Labeled Compounds	Others
Roxithromycin-d₇ (RU-28965-d₇)is the deuterium labeledRoxithromycin(HY-B0435) . Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic .

HY-B0136

Cefdinir 1 Publications Verification FK-482; CI-983	Bacterial Antibiotic	Infection
Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .

HY-17412S1

Minocycline-d6 sulfate	Isotope-Labeled Compounds	Infection Neurological Disease Inflammation/Immunology Cancer
Minocycline-d₆ sulfate is deuterated labeled Minocycline (HY-17412A). Minocycline is an orally effective semi-synthetic tetracycline antibiotic and HIF-1α inhibitor that can penetrate the blood-brain barrier. Minocycline has bacteriostatic, anti-cancer, anti-inflammatory, neuroprotective properties and antidepressant effects.

HY-P2834

Penicillin amidase, E. coli PGA	Biochemical Assay Reagents	Infection
Penicillin amidase (EC 3.5.1.11) (Penicillin acylase) is an enzyme that cleaves the acyl side chains of penicillins. Penicillin amidase can be used for the production of 6-aminopenicillanic acid. Penicillin amidase can also be used in the resolution of racemic mixtures, peptide synthesis, and synthesis of semi-synthetic β-lactam antibiotics .

HY-139554A

Zifanocycline TFA KBP-7072 TFA	Bacterial	Infection
Zifanocycline (KBP-7072) TFA is an orally active, semi-synthetic aminomethylcycline antibiotic that inhibits the normal function of bacterial ribosomes. Zifanocycline TFA has broad spectrum in vitro antimicrobial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline TFA is indicated for the study of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections .

HY-17412

Minocycline hydrochloride Maximum Cited Publications 31 Publications Verification	Bacterial Antibiotic HIF/HIF Prolyl-Hydroxylase Apoptosis MDM-2/p53 Potassium Channel Calcium Channel	Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Minocycline hydrochloride is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline hydrochloride is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline hydrochloride shows *anti-cancer, anti-inflammatory, and glutamate* antagonist effects. Minocycline hydrochloride reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline hydrochloride inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .

HY-17412A

Minocycline	Antibiotic Bacterial HIF/HIF Prolyl-Hydroxylase Apoptosis MDM-2/p53 Potassium Channel Calcium Channel	Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows *anti-cancer, anti-inflammatory, and glutamate* antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .

HY-17412R

Minocycline hydrochloride (Standard)	Bacterial Antibiotic HIF/HIF Prolyl-Hydroxylase Apoptosis MDM-2/p53 Potassium Channel Calcium Channel	Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Minocycline (hydrochloride) (Standard) is the analytical standard of Minocycline (hydrochloride). This product is intended for research and analytical applications. Minocycline hydrochloride is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline hydrochloride is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline hydrochloride shows *anti-cancer, anti-inflammatory, and glutamate* antagonist effects. Minocycline hydrochloride reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline hydrochloride inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .

HY-B2091

Azidocillin
Azidocillin, a semi-synthetic Penicillin, is an orally active β-lactam *antibiotic. Azidocillin bears an azide functionality and retains on-target activity within bacteria*. Azidocillin can be used to research osteitis caused by dental surgery, otitis media, enterococcal septicemia and other bacterial infectious diseases . Azidocillin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-B0408A

Clindamycin hydrochloride 5 Publications Verification	Bacterial Antibiotic	Infection Cancer
Clindamycin (hydrochloride) is a semisynthetic lincosamide antibiotic, which inhibits protein synthesis by acting on the 50S ribosomal.

HY-N6670

Cefotetan

Bacterial Antibiotic Infection

Cefotetan is a semisynthetic cephamycin antibiotic that exerts its bactericidal effects by inhibition of cell-wall synthesis .

Cefotetan	Bacterial Antibiotic	Infection
Cefotetan is a semisynthetic cephamycin antibiotic that exerts its bactericidal effects by inhibition of cell-wall synthesis .

HY-17025

Rifabutin 4 Publications Verification Ansamycin; LM-427	Bacterial Antibiotic	Infection
Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-108879

Cefotetan disodium	Bacterial Antibiotic	Infection
Cefotetan disodium is a semisynthetic cephamycin antibiotic that exerts its bactericidal effects by inhibition of cell-wall synthesis .

HY-N7102

Ceftiofur 3 Publications Verification	Bacterial Antibiotic	Infection
Ceftiofur is a semisynthetic antibiotic, with activity against various gram-positive and gram-negative, aerobic and anaerobic bacteria encountered by domestic animals .

HY-B0026

Ceftiofur hydrochloride	Bacterial Antibiotic	Infection
Ceftiofur hydrochloride is a semisynthetic antibiotic, with activity against various gram-positive and gram-negative, aerobic and anaerobic bacteria encountered by domestic animals .

HY-B1466

Mezlocillin sodium BAY-f 1353 sodium	Bacterial Antibiotic	Infection
Mezlocillin (BAY-f 1353) sodium is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin sodium is active against both gram-negative and gram-positive bacteria. Mezlocillin sodium can be used in bacterial infection research .

HY-B1466A

Mezlocillin BAY-f 1353
Mezlocillin (BAY-f 1353) is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin is active against both gram-negative and gram-positive bacteria. Mezlocillin can be used in bacterial infection research .

HY-17025S

Rifabutin-d7 Ansamycin-d₇; LM-427-d₇	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Rifabutin-d₇ is the deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-145158

Temocillin	Bacterial Antibiotic	Infection
Temocillin, a 6-alpha-methoxy penicillin derivative, is a semisynthetic beta-lactam antibiotic with a spectrum of activity against most aerobic Gram-negative bacteria .

HY-B0875

Cefmenoxime hydrochloride SCE-1365 hydrochloride	Antibiotic Bacterial	Infection
Cefmenoxime (SCE-1365) hydrochloride is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria .

HY-B0875A

Cefmenoxime SCE-1365
Cefmenoxime (SCE-1365) is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria .

HY-B0408AR

Clindamycin hydrochloride (Standard)	Bacterial Antibiotic	Infection Cancer
Clindamycin (hydrochloride) (Standard) is the analytical standard of Clindamycin (hydrochloride). This product is intended for research and analytical applications. Clindamycin (hydrochloride) is a semisynthetic lincosamide antibiotic, which inhibits protein synthesis by acting on the 50S ribosomal.

HY-B0529

Azlocillin	Bacterial Parasite Antibiotic	Infection
Azlocillin, an *antibiotic, is a semisynthetic* penicillin, and has broad-spectrum antibacterial activity. Azlocillin is active against drug-tolerant B. burgdorferi sensu stricto JLB31 infection .

HY-B0529A

Azlocillin sodium salt Sodium azlocillin	Bacterial Parasite Antibiotic	Infection
Azlocillin sodium salt (Sodium azlocillin), a semisynthetic penicillin, is a broad spectrum β-lactam *antibiotic. Azlocillin sodium salt shows antipseudomonal activity, and also potent against the malarial parasite* Plasmodium falciparum .

HY-17586

Dalbavancin hydrochloride 5+ Cited Publications MDL-63397 hydrochloride; BI-397 hydrochloride	Bacterial Antibiotic	Infection
Dalbavancin hydrochloride (MDL-63397 hydrochloride) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin hydrochloride inhibits *Staphylococcus aureus* and *Bacillus anthracis* with MIC₉₀s of 0.06 μg/mL and 0.25 μg/mL, respectively .

HY-17586A

Dalbavancin MDL-63397; BI-397	Bacterial Antibiotic	Infection
Dalbavancin (MDL-63397) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin inhibits *Staphylococcus aureus* and *Bacillus anthracis* with MIC₉₀s of 0.06 μg/mL and 0.25 μg/mL, respectively .

HY-34588

D-4-Hydroxyphenylglycine D-(-)-4-Hydroxyphenylglycine; 4-Hydroxy-D-phenylglycine	Others	Others
D-4-Hydroxyphenylglycine (D-(-)-4-Hydroxyphenylglycine) is one of the most important raw materials used in the production of semisynthetic β-lactam antibiotics, such as Amoxicillin (HY-B0467A) and Cefadroxil (HY-B1190) .

HY-19906

LFF-571
LFF-571 is an orally active semisynthetic thiopeptide *antibiotic. LFF-571 shows potent activity against a Clostridium difficile* and Staphylococcus aureus with MIC values of 0.03 and 0.125 μg/mL, respectively. LFF-571 can be used for the research of infection .

HY-B1286

Piperacillin sodium 5 Publications Verification Sodium piperacillin	Bacterial Antibiotic Penicillin-binding protein (PBP)	Infection
Piperacillin sodium is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .

HY-B1923

Piperacillin 5 Publications Verification Pipracil
Piperacillin is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .

HY-17586AS

Dalbavancin-d6 MDL-63397-d₆; BI-397-d₆	Bacterial Antibiotic	Infection
Dalbavancin-d₆ is the deuterium labeled Dalbavancin[1]. Dalbavancin (MDL-63397) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively[2][3].

HY-B1257

Cefmetazole sodium Sodium cefmetazole	Bacterial Antibiotic	Infection
Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin *antibiotic* with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .

HY-B1595

Cefmetazole CS 1170
Cefmetazole (CS 1170) is a semisynthetic cephamycin *antibiotic* with broad-spectrum antibacterial activity, covering gram-positive, gram-negative and anaerobic bacteria. Cefmetazole binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .

HY-B0200

Cephalexin 5+ Cited Publications Cefalexin; Cephacillin	Penicillin-binding protein (PBP) Antibiotic Bacterial	Infection Cancer
Cephalexin (Cefalexin) is a potent, orally active semisynthetic cephalosporin *antibiotic* with a broad antibacterial spectrum. Cephalexin has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al .

HY-B0509

Amikacin hydrate 5+ Cited Publications BAY 41-6551 hydrate	Bacterial Antibiotic	Infection Cancer
Amikacin hydrate (BAY 41-6551 hydrate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin hydrate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin hydrate is very active against most Gram-negative bacteria including gentamicin- and tobramycin-resistant strains. Amikacin hydrate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria .

HY-B0200A

Cephalexin hydrochloride 5+ Cited Publications Cefalexin hydrochloride; Cephacillin hydrochloride	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection Cancer
Cephalexin (Cefalexin) hydrochloride is a potent, orally active new semisynthetic cephalosporin *antibiotic* with a broad antibacterial spectrum. Cephalexin (Cefalexin) hydrochloride has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) hydrochloride targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin (Cefalexin) hydrochloride is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al .

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